The have split their last six meetings with the , ending a three-game slide with a 31-17 road win in their most recent clash on Dec. 1, 2019. However, the Titans franchise is 16-34 in its 50 regular-season contests against the Colts thanks to an 11-game losing streak from 2011 to 2016, and has dropped seven of the last eight matchups at home. Tenne see hopes for a favorable result when it hosts Indianapolis on Thursday Night Football. Kickoff from Ni san Stadium in Nashville is scheduled for 8:20 p.m. ET.The Titans (6-3) have fared well at home in 2020, improving to 4-1 with a 24-17 win over Chicago last week. Indianapolis (5 Pedro Martinez Jersey -3), which was defeated 24-10 by Baltimore at home on Sunday, is seeking its third victory in its last four road games. Thursday Night Football is a pick'em in the latest Titans vs. Colts odds from William Hill Sportsbook, while the over-under is 48.5. Before locking in any Colts vs. Titans picks, make sure you .The model, which simulates every NFL game 10,000 times, is up over $7,600 for $100 players on top-rated NFL picks since its inception five-plus years ago. It's off to a strong 16-9 roll on top-rated NFL picks this season. The model enters Week 10 on an incredible 112-74 run on top-rated NFL picks that dates back to the 2017 season.The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.Now, the model has set its sights on . You can . Here are the from William Hill and trends for Titans vs. Colts:Titans vs. Colts spread: PKTitans vs. Colts over-under: 48.5 pointsTitans vs. Colts money line: Tenne see -105, Indianapolis -115TEN: Titans are 2-5 against the spread in their last seven games as favoritesIND: Over has hit in three of last four Colts gamesWhy the Titans can coverTenne see has one of the top offenses in the NFL, ranking sixth in rushing (147.6 yards) and seventh in scoring (29 points). The Titans are 10th in total offense (384.6 yards) and lead the league in turnover differential at plus-10. The ground attack is buoyed by , who was the 2019 rushing champion with a career-high 1,540 yards.The 26-year-old Henry is second in the NFL this season with 843 yards, 15 fewer than Minnesota's , and tied for third with eight rushing touchdowns.Wide receiver A.J. Brown (team-high 457 yards) and tight end share the club lead with six receiving TDs after recording one apiece against the . Linebacker , who has yet to register a sack in his first season with the Titans, is expected to play Thursday after mi sing last week's game with a knee injury.Why the Colts can cover has thrown only 10 touchdown pa ses and seven interceptions in his first season with Indianapolis but has a succe sful history against the Titans franchise. In nine career meetings, the 38-year-old completed 70.4 percent of his pa s attempts while leading the to seven victories.Indianapolis hopes to have wide receiver T.Y. Hilton on the field after he mi sed the lo s to the with a groin injury. Hilton, who has been a full participant in practice this week, has hauled in 61 pa ses for 941 yards and five TDs in 15 career games against Tenne see.How to make Titans vs. Colts picksSportsLine's model is leaning under. In fact, it's calling for 47 total points. It also says one side of the spread hits well over 50 percent of the time. .So who wins Colts vs. Titans on Thursday Night Football? And which side of the spread hits well over 50 percent the time? , and find out. Keith Hernandez Jersey